TexRAD Attends RSNA 2015

TexRAD attended the 101st scientific assembly and annual meeting of the Radiological Society of North America on the 29th November to 4th December 2015 at the McCormick Place in Chicago, USA. 

This year at the RSNA there were around 5 presentations from our customer sites spread across USA, Canada, UK and the EU. These talks and posters covered different research applications in the area of oncology. A brief list of the individual presentations is provided as below.

(Note the RSNA program is here: https://rsna2015.rsna.org/program/. Searching on the Session ID  in the table below will take you straight to the relevant part of the program.)

Session ID Details
SSA10-08 Sunday 10:45-12:15 PM | SSA10 | E353B

Prediction of Survival in Patients with Metastatic Clear Cell Carcinoma Treated with Targeted Anti-angiogenic Agent Sunitinib via CT Texture Analysis

Masoom A. Haider, MD | Alireza Vosough, MD, MRCP | Farzad Khalvati, PhD,MSc | Alexander Kiss, PhD | Balaji Ganeshan, PhD | Georg Bjarnason, MD

 IN246-SD-MOB2  Monday 12:45-1:15 PM | INS-MOB | IN Community, Learning Center

Evidence of a ‘Tumor Signature’ in Metastasis by Quantitative Texture Analysis of CT-Scan Images

Laurent Dercle, MD | Charles Ferte, | Cyril Jaudet, PhD | Eva Haspinger | Jean-Charles Soria, | Samy Ammari,

 SSE07-06  Monday 3:00-4:00 PM | SSE07 | E353A

Characterization of Portal Venous Thrombus (Bland vs Neoplastic) on CT Using Software Based Textural Analysis

Rodrigo Canellas, MD | Farhad Mehrkhani, MD | Manuel Patino, MD | Andrea Prochowski Iamurri, MD | Avinash R. Kambadakone, MD | Dushyant V. Sahani, MD

 MI233-SD-THA3  Thursday 12:15-12:45 PM | MIS-THA | S503AB

Tumor Heterogeneity Measured on Pre-treatment PET/CT Predicts Overall Survival in Patients with Anal Squamous Cell Carcinoma

Asim Afaq, FRCR | Balaji Ganeshan, PhD | Tal Grenader | Gabrielle Azzopardi | Raymondo Endozo, | John Bridgewater | Ashley M. Groves, MBBS

 SST06-08  Friday 10:30-12:00 PM | SST06 | E353C

Association of Tumor Heterogeneity on CT Image with Genetic Mutation of the Isocitrate Dehydrogenase and Survival in Cholagiocarcinoma

Koichi Hayano, MD | Lipika Goyal, MD | Andrew X. Zhu, MD, PhD | Rahmi Oklu, MD, PhD | Cinthia Cruz, MD | Manuel Patino, MD | Dushyant V. Sahani, MD

TexRAD attends ECR 2015

TexRAD related talks and presentations were very well received at the recently concluded European Congress of Radiology (ECR) – scientific assembly and annual meeting of the European Society of Radiology from the 4th March to 8th March 2015 at the Austria Center in Vienna, Austria. It was quite evident at the conference that texture analysis is growing in importance as tool for the assessment of heterogeneity within tumours and other non-tumour applications (fibrosis, neurological/psychiatric disorders, cardiology) and as a risk-stratification tool having diverse applications (prognosis, disease-severity/characterization of lesions, treatment response prediction and evaluation), and is potentially leading to be an important non-invasive clinical imaging tool for tomorrow.
Presentations on TexRAD covered quite a diverse range of areas to validate this as a novel imaging biomarker (detailed in the table below).
The talk on Wed 4 March demonstrated the biological-correlate for multiparametric PET-CT image quantification (which includes TexRAD CT-texture-analysis) in terms of immuno-histochemical analysis (hypoxia, angiogenesis, ALK expression) in lung cancer.
The talk on Fri 6 March demonstrated the treatment response-prediction and evaluation ability of TexRAD MR-T2 texture analysis in assessing neo-adjuvant chemo-radiotherapy better than MR perfusion and diffusion in rectal cancer.
The talk on Sunday 8 March demonstrated the prognostic-ability of pre-operative TexRAD CT texture analysis of liver metastases in patients with colorectal liver metastases post liver resection. This paper was further recommended by the ECR 2015 Congress President (Prof. Bernd Hamm) and published as a full-page article in ‘ECR today’ on Sunday March 8 bulletin (in the clinical corner section). The paper was also voted as the best paper in the scientific session (Liver CT and ultrasound: New Technique – Abdominal Viscera, Imaging methods) where it was presented amongst the other science presentations.
The E-poster demonstrated a novel robust radiomics-approach using breast cancer patient population as an example, where multiparametric PET-CT features showed strong associations with immuno-histochemistry and identified high-risk patients (having – high mortality-risk, high tumour grade, high expression of proliferation marker – mcm2, high proportion of estrogen receptor negative status).

Session

Details

SS 216 Thoracic Oncology (Chest, Oncologic Imaging) 

Wed Mar 4 2015 11:18AM – 11:26AM ROOM F1
B-0093 – Multi-parametric PET-CT correlates with hypoxia, angiogenesis and ALK expression in non-small cell lung cancer
D. Neriman, B. Ganeshan, A. Groves; London/UK

 

SS 1001 Rectal cancer and anorectal imaging (GI Tract, Oncologic Imaging)

Fri Mar 6 2015 10:47AM – 10:55AM ROOM F2
B-0833 – Performance of Texture Analysis, Diffusion Weighted Imaging and Perfusion Imaging in Predicting Tumoral Response to Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients Studied with 3-T MR
M. Ciolina, C. De Cecco, B. Ganeshan, M. Rengo, D. Bellini, A. Laghi; Rome/IT, Latina/IT, London/UK

 

SS 1901b       Liver CT and ultrasound: New Technique (Abdominal Viscera, Imaging Methods)

Sun Mar 8 2015 14:00 – 14:08 ROOM M
B-1196 – Preoperative CT Texture analysis predicts outcome in patients with colorectal liver metastases post liver resection***
A.    Schulz, K. Skogen, A. Bethke, K.J. Labori, B. Ganeshan, N.-E. Klow, J.B. Dormagen; Oslo/NO, London/UK
***This paper and the findings upon recommendation by Prof. Bernd Hamm, ECR 2015 Congress President is going to be further highlighted in the daily bulletin – ‘ECR Today 2015’ during the congress.

 

Poster: C-1320

Tues Dec 02 2014 11:10AM – 11:20AM ROOM S402AB
Multi-parametric PET-CT in breast cancer: association with histopathology and survival-risk
B. Ganeshan, M. Keshtgar, K. Miles, R. Endozo, M. Rodriguez-Justo, M. Meagher, A. Malhotra, S. Chua, A. Groves; London/UK, Sutton/UK

 

TexRAD to Attend RSNA 2014

TexRAD is attending the 100th scientific assembly and annual meeting of the Radiological Society of North America on the 30th November to 5th December 2014 themed ‘A century of transforming medicine’ at the McCormick Place in Chicago, USA. 

Dr. Balaji Ganeshan will be presenting a number of TexRAD related papers particularly in colorectal cancer prognosis and response evaluation at RSNA. The details of papers and presentations related to TexRAD to be presented at RSNA this year are given below.

We hope to meet you at the RSNA meeting. Please email us (info@texrad.co.uk / balaji@texrad.co.uk) to specify some convenient dates and times and we will ensure that Dr. Balaji Ganeshan (Scientific-Director, TexRAD Ltd) and/or Mike Hayball (Managing-Director CCI Ltd) are able to give you their full attention. We can give a TexRAD scientific presentation and software demonstration (which includes Texture-processor and a novel Data-Mining tool to undertake the statistical analyses and identify interesting parameters leading to research publications!). In addition, we will discuss how TexRAD can assist you to enhance your research output in your specific areas of interest similar to the number of other prestigious research and clinical institutions around the world.

In addition, we will be attending Her Majesty’s Consul General’s reception at 6pm on Monday December 1st.

We look forward to hearing from you and meeting with you at RSNA!

Session

Details

SSA07-04

Sun Nov 30 2014 11:15AM – 11:25AM ROOM E450A

MRI Tumor Heterogeneity as a Potential Prognostic Imaging Biomarker in Patients with Rectal Cancer Treated with Neoadjuvant Chemoradiotherapy

Omer Jalil | Balaji Ganeshan PhD | Asim Afaq FRCR | Tan Arulampalam | Darren Boone MRCS, FRCR |Ashley M. Groves MBBS

SSA07-06

Sun Nov 30 2014 11:35AM – 11:45AM ROOM E450A

Performance of Texture Analysis, Diffusion Weighted Imaging and Perfusion Imaging in Predicting Tumoral Response to Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients Studied with 3T MR

Carlo Nicola de Cecco MD | Maria Ciolina MD | Balaji Ganeshan PhD | Marco Rengo MD | Luca Saba MD |Andrea Laghi MD

SSG07-01

Tues Dec 02 2014 10:30AM – 10:40AM ROOM S402AB

Classification of Renal Masses Using CT Texture Analysis: Generation of A Predictive Model on the Basis of Quantitative Spatial Frequency Measurements and Random Forest Modeling

Siva P. Raman MD | Yifei Chen BS | James L. Schroeder PhD | Peng Huang | Elliot K. Fishman MD

SSG07-05

Tues Dec 02 2014 11:10AM – 11:20AM ROOM S402AB

CT Texture Analysis of Histologically Proven Benign and Malignant Lung Lesions

Roberto Lo Gullo MD | Mannudeep K. Kalra MD | Atul Padole MD | Alexi Otrakji MD | Jo-Anne O. Shepard MD | Subba R. Digumarthy MD | Sarabjeet Singh MD | Ranish Deedar Ali Khawaja MD

MIS136

Tues Dec 05 2014 12:45PM-01:15PM ROOM S503AB

Role of Tumor Texture Analysis on CT Image and Tumor Metabolism Measured by FDG-PET in the Management of Non-small Cell Lung Cancer Patients

Koichi Hayano MD | Naveen Kulkarni MD | Fang Tian MD | Dushyant V. Sahani MD

SSJ20-01

Tue Dec 02 2014 3:00PM – 3:10PM ROOM S505AB

18F-FDG PET: An Independent Prognostic Biomarker in Idiopathic Pulmonary Fibrosis

Thida Win | Nicholas J. Screaton BMBCh | Joanna C. Porter PhD, FRCP | Balaji Ganeshan PhD | Lynn Millner | Ashley M. Groves MBBS

SSM06-01

Wed Dec 03 2014 03:00PM – 03:10PM ROOM S404CD

Non Small Cell Lung Cancer: Efficacy of CT Texture Analysis in Assessment of Histological Subtype

Roberto Lo Gullo MD | Mannudeep K. Kalra MD | Alexi Otrakji MD | Lecia Sequist | Jo-Anne O. Shepard MD| Subba R. Digumarthy MD | Zofia Piotrowska

SSQ06-05

Thu Dec 04 2014 11:10AM – 11:20AM ROOM E350

PETCT Derived Tumoural Heterogeneity and Glucose Uptake Predicts Survival in Primary Colorectal Cancer Patients

Ming Young S. Wan MBBChir | Balaji Ganeshan PhD | Alec Engledow | Daren Francis | Nick Reay-Jones | Manuel Rodriguez-Justo | Marie Meagher | Jacquie Peck | Kim Jaggs | Helen Whiteway | Jackie Hayward | Zia Saad | Faira Rizal |Jakub Nalepa | Michael Hayball | Robert Kozarski | Peter J. Ell MD | Stuart A. Taylor MBBS | Steve Halligan MD | Kenneth Miles | Ashley M. Groves MBBS

INS169

Thu Dec 04 2014 12:15PM – 12:45AM ROOM IN Community, Learning Center

Texture Analysis with Predictive Modeling of Solid Appearing Pancreatic Serous Cystadenomas versus Neuroendocrine Tumors

Franco Verde MD | Siva P. Raman MD | Linda C. Chu MD | Yifei Chen BS | Peng Huang | Elliot K. Fishman MD