Dr Balaji Ganeshan presented and gave a demonstration of TexRAD as part of the topic ‘Advances in Medical Imaging’ at the college’s department of radiology on the 3rd of January 2018.
The talk was titled “Quantifying Tumour Heterogeneity with TexRAD Texture Analysis on CT and MRI – Ready for Prime Time?”
Tumour heterogeneity is a well-recognised feature of malignancy associated with increased tumour aggression and treatment resistance. It can be evaluated at genetic, epigenetic and phenotypical levels. Heterogeneity can alter biological and physical factors such as vascularity (angiogenesis), necrosis, fibrosis, proliferation and hypoxia etc. Texture analysis of diagnostic images such as CT, MRI and PET can quantify and provide an objective measurement of heterogeneity which can assist in radiological and oncological practice. TexRAD is a well established and widely published technique of Texture analysis.
The talk’s key discussion points included:
· What does TexRAD texture analysis actually mean?
· Biological correlates
· Clinical validation – prognosis, disease-severity, treatment-response/prediction
· Technical validation
· Clinical utility and cost-effectiveness